Formulation and evaluation of antibacterial and antioxidant herbal cream of curry leaves and turmeric extract

Priya Thakur *, Sahil Thakur, Kajal, Shivam Thakur, Mohit Sharma, Kumari Varsha, Sunaina Dhiman and Sunil Kumar

Gautam College of Pharmacy, Hamirpur, Himachal Pradesh, India. 
 
Research Article
World Journal of Advanced Research and Reviews, 2024, 22(01), 170–184
Article DOI: 10.30574/wjarr.2024.22.1.1011
 
Publication history: 
Received on 22 February 2024; revised on 28 March 2024; accepted on 31 March 2024
 
Abstract: 
Humanity relies on plants to meet its basic needs, such as food, clothing, and shelter. Both rural and urban civilizations benefit from wild plants for medicinal, craft, and beauty purposes. Murraya kienigii Linn (Rutaceae), also known as Meethi Neem or Curry Patta, is a fragrant, usually deciduous shrub or small tree that can grow to be 6 meters tall. It may be found all throughout India and reaches heights of up to 1500 meters. It is cultivated for its fragrant leaves. In traditional medicine, it is used as an antiemetic, antidiarrheal, dysentery, febrifuge, blood purifier, tonic, stomachic, and flavoring agent in curries and chutneys. The essential oil derived from the leaves contains alkaloids such as mahanine, koenidine, koenigine, koenine, girinimibine, girinimbiol, murrayamine, and several more.
Another plant Turmeric (Curcuma longa L.) belongs in the ginger family, which is native to Southwest India. Turmeric is a medicinal and fragrant plant that is recognized as one of nature's most valuable resources, with enormous export potential in medicine, personal care, culinary spices, and natural colours. An ethanolic extract of turmeric including curcumin, dimethoxy-curcumin, and bisdemethoxycurcumin has been shown to reduce blood glucose levels in mice and prevent blood glucose from rising. Reduces proteinuria and haematuria when taken orally in people with refractory lupus nephritis. Curcuminoid is the most abundant component in turmeric, along with many other phenolic compounds and mono-, sesqui-terpenes.
Soxhlet extraction combines both percolation and maceration techniques. The extraction is carried out using a particular device known as the Soxhlet apparatus, which was created by Franz von Soxhlet in 1879. It was one of the most popular extraction methods, and it is still commonly used today. The apparatus comprises of an extraction chamber linked to a vapor duct and a siphon tube that continues down to the joint, where a circular bottom shell may be attached. A thimble of filter paper or a cotton plug is put in the extraction chamber to prevent the siphon tube from being blocked when powdered medication material is introduced. In this extraction we will use the Soxhlet extraction method to extract the phytoconstituents of the respective plants.
 
Keywords: 
Murraya Koenigii; Curcuma longa L.; Anti- bacterial; Anti-oxidant; Herbal cream.  
 
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