To study the Helicobacter pylori infection in peptic ulcer
1 Department of Pharmacology, Saastra College of Pharmaceutical Education and Research, Near Varigonda Jwalamukhi Temple, MuthukurRaod, Kakupalli, Nellore-524311, Andhra Pradesh, India.
2 Saastra College of Pharmaceutical Education and Research, Near Varigonda Jwalamukhi Temple, Muthukur Raod, Kakupalli, Nellore-524311, Andhra Pradesh, India.
3 Department of Pharmaceutics, Saastra College of Pharmaceutical Education and Research, Near Varigonda Jwalamukhi Temple, Muthukur Raod, Kakupalli, Nellore-524311, Andhra Pradesh, India.
Review Article
World Journal of Advanced Research and Reviews, 2024, 22(01), 1801-1808
Article DOI: 10.30574/wjarr.2024.22.1.1098
Publication history:
Received on 14 March 2024; revised on 24 April 2024; accepted on 26 April 2024
Abstract:
Helicobacter pylori is a gram negative bacterium which causes chronic gastritis and plays important roles in peptic ulcer disease, gastric carcinoma, and gastric lymphoma. Its major in the human pathogen that produces inflammation of the stomach and etiologically related to the duodenal ulcer, gastric ulcer, gastric cancer and mucosa-lymphoid tissue. It is weakens the protective mucous coating of the stomach and duodenum, thus allowing acid to get through to the sensitive lining beneath. Both the acid and the bacteria irritate the lining and cause a sore, or ulcer. Helicobacter treated with a combination of antibiotics plus a proton pump inhibitor. Peptic ulcer is characterized by discontinuation in the inner lining of the gastrointestinal tract because of the gastric acid secretion or pepsin. It extends into muscularis propria layer of the gastric epithelium. It usually occurs in the stomach and proximal duodenum. Peptic means that cause of the problem is due to the acid. It is most common causes in the peptic ulcers are infection with the bacterium and causes the long-term use of the non-steroidal anti-inflammatory drugs. Gastric ulcer occurs in the stomach. Duodenal ulcer occurs in the first part of the small intestine. The interplay of gastritis phenotype related to the bacterium colonization and resulting acid secretion.
Keywords:
Antibiotic; Infection; Treatment; Vaccine; Immune responses
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